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Hypochlorous acid is naturally produced by the body’s immune system.1-2 This molecule can also be synthesized chemically, for example, by electrolysis as in the case of Puracyn Plus Professional Formula. Below is a list of available scientific texts and publications regarding biological function of hypochlorous acid.
1. Weiss SJ, Lampert MB, Test ST. Long-lived oxidants generated by human neutrophils: characterization and bioactivity. Science. 1983; 222: 625-628
2. Kleanoff SJ, Myeloperoxidase: contribution to the microbiocidal activity of intact leukocytes. Science. 1970; 169(950): 1095-1097
3. Nakae H, Inaba H. Effectiveness of electrolyzed oxidized water irrigation in a burnwound infection model. J. Trauma. 2000; 49(3): 511-512
4. Sakarya S, Gunay N, Karakulak M, Ozturk B, Ertugrut B. Hypochlorous acid: an ideal wound care agent with powerful microbicidal, antibiofilm, and wound healing potency. Wounds. 2014; 26(12): 342-350
Hypochlorous acid has been primarily used in wound cleansing solutions as an antimicrobial preservative to inhibit the growth of microorganisms within the product in case of contamination during storage or use. However, additional clinical benefits of products containing hypochlorous acid have been reported. Below is an available scientific publication regarding the clinical use of hypochlorous acid.
Bongiovanni CM. Effects of Hypochlorous Acid Solutions on Venous Leg Ulcers (VLU): Experience With 1249 VLUs in 97 Patients. J Am Coll Clin Wound Spec. 2016 Jan 21;6(3):32-7
Hypochlorous acid has also been used as the active ingredient in EPA-approved disinfectants in a broad range of applications including surface sanitization and disinfection needs in hospitals and healthcare facilities.
Hypochlorous acid, being electrically neutral in solution, is significantly more efficacious in killing microorganisms than common bleach solution which is electrically negative in solution. The cell wall of a pathogenic microorganism is negatively charged by nature. The negative charge of a bleach molecule would be repulsed by the cell wall, making it a weak disinfectant. On the other hand, the neutral hypochlorous acid molecule can penetrate the cell wall of pathogenic microorganisms easily, making it a very effective disinfectant. Hypochlorous acid can also penetrate slime layers and protective layers of microorganisms as a result.
For more information about hospital-grade disinfectants, please send your inquiry to: info@skvscientific.com (SKV Scientific, Inc.)
